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Liverpool, on the other hand, will be hoping to continue their great run at home, with the Reds playing 67 games at Anfield without defeat.
On the likelihood of Jordan Henderson again being deployed in central defence if Matip is not available, Klopp added: “We have still different solutions.
“Hendo is very important in midfield for us as well, so we just have to see. It’s not decided yet, why should I?”
“The next one is always the biggest, it’s always the most important,” Solskjaer said.
“Being, of course, where we are in the league, that just gives us more confidence and it’s an indication of where we’re at.
Naby Keita is definitely ruled out of the 4.30pm GMT kick-off, however.
Klopp said of the No.8’s fitness: “Now we just had to put on the brake and say, ‘Let’s settle it properly.’ In the moment we have alternatives in midfield, so we really try to give him all the time he needs to get 100 per cent fit.”
Thiago Alcantara is in line to make his Anfield debut for the club, while Divock Origi and Xherdan Shaqiri could reach the milestones of 150 and 50 Liverpool appearances respectively.
“But the game against the champions, they’ve got an amazing record at Anfield in the league. They haven’t lost for many, many years so of course it’s a great test for us. Can we go there and cause an upset?”
“He had now 90 and 45 minutes in the last two games,” Klopp noted on Thiago. “So, we will see if he can play, which position he will play because there are obviously different options and all that stuff.”
Liverpool vs Man Utd
And although the clash of north-west rivals always attracts huge interest regardless of their league positions, you’d be crazy to deny that this weekend’s meeting doesn’t carry additional importance.
That’s because United and Liverpool entered the current game-week in first and second place respectively, emerging as the early frontrunners to be crowned champions of England.
Now, I think we can all agree that Liverpool are more favoured to achieve what they did last season and their unbeaten league run at Anfield is fast-approaching a rather astonishing four years.